Chemical Products Adefovir Dipivoxil Tablets Product Usage

CAS No:106941-25-7
Formula:C8H12N5O4P
Synonyms:ADEFOVIR DIPIVOXIL
China Export:From 2018.11 to 2019.11, total export volume of Adefovir Dipivoxil Tablets from China was 112,377,052KG while total export value was $2,146,929,254. The biggest proportion of exporting volume in the last 12 months was 9.88% in 2019.03.

Chemical Products Adefovir Dipivoxil Tablets Description
Adefovir (GS-0393) is an adenosine monophosphate analog antiviral agent that after intracellular conversion to Adefovir diphosphate inhibits HBV DNA polymerase. Adefovir has an IC50 of 0.7 μM against HBV in the HepG2.2.15 cell line. Adefovir has good antiviral activity against several viruses, including HBV and herpesviruses[1][2][3].

Chemical Products Adefovir Dipivoxil Tablets Basic Attributes
CAS No：106941-25-7

Molecular Formula ：C8H12N5O4P

Molecular Mass ：273.19

Exact Mass ：273.062683

PSA ：136

LogP ：-2

EINECS ：1806241-263-5

InChIKeys ：SUPKOOSCJHTBAH-UHFFFAOYSA-N

H-bond Acceptor ：8

H-bond Donor ：3

SP3 ：0.38

RBN ：5

Chemical Products Adefovir Dipivoxil Tablets Characteristics
Appearance ：white to beige

Density ：1.88

Melting Point ：>260°C

Flash Point ：336.3±34.3 °C

Refractive Index ：1.769

Solubility ：0.1 M NaOH: ≥5mg/mL

Storage Condition ：-20°C Freezer

Vapor Pressure ：6.06X10-11 mm Hg at 25 deg C (est)

Chemical Products Adefovir Dipivoxil Tablets Safety Information
Packing Group ：III

Hazard Class ：6.1

HS Code ：2933990090

UN No. ：2811

WGK_Germany ：2

Risk Code ：25

Safety Instructions ：45

RTECS No. ：SZ6563500

Dangerous Mark ：T

P Code ：P301 + P310

Hazard Statements ：H301

Chemical Products Adefovir Dipivoxil Tablets Product Usage
Used as an antiviral